Coats’ disease, also known as Exudative Retinitis or exudative retinopathy.  It is a progressive condition of the retinal capillaries which occurs in children and young adults, usually males. Commencing typically during the first decade of life, it is gradual in progress and affects central vision, usually in only one eye.

Retinal capillaries play an important part in the nourishment of the retina which forms the thin light-sensitive screen lining the inside of the back two thirds of the eye. Light reaching the retina is converted into electrical impulses which pass along the optic nerve to the brain where the impulses are converted to sight.

Also known as:
Morbus coats
Coats’ retinitis
Coats’ syndrome

Exudative retinitis, exudative retinopathy, retinitis circinata, retinitis exudativa, retinitis exudativa externa, retinitis haemorrhagica externa, retinal telangiectasia

Mutations in the Norrie Disease (ND) gene are associated with a spectrum of retinal findings ranging from Norrie disease (ND) to X-linked familial exudative vitreoretinopathy (FEVR), including some cases of persistent hyperplastic primary vitreous (PHPV), Coats disease, and advanced retinopathy of prematurity (ROP). Rarely, carrier females can evidence a clinical phenotype. These phenotypes appear to be a continuum of retinal findings with considerable overlap (Table 1). The ocular findings that permit a presumptive diagnosis of an ND-spectrum disorder include the following: MORE ON MUTATION OF NORRIE DISEASE CAUSING COATS


Coats’ Disease (also known as Exudative Retinitis) factsheet

Coats Disease – Article from eMedicine

Coats disease by Doctor Alessandra Del Longo


  • G. Coats:
    Forms of retinal disease with massive exudation.
    Royal London Ophthalmic Hospital Reports, 1908, 17, 3: 440-525.
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